Neil Lennon has even deeper injury worries in attack in the aftermath of the 0-0 draw with Liverpool, as Emile Heskey joined Craig Davies, Zach Clough, Max Clayton, Mark Davies and Chung Yong-Lee on Wanderers' extensive injury list. This means a return to the starting lineup for youngster Conor Wilkinson supported by Eidur Gudjohnsen, who starts despite completing 90 minutes at Anfield just 72 hours ago.
But the big news for Wanderers tonight is a full debut for young left-sided Academy product Andy Kellett, who impressed during a loan spell at Plymouth Argyle in the first half of this season. The 21-year-old appears likely to start on the left of midfield for Wanderers, with Josh Vela set to return to right-back alongside Saturday night's heroes Matt Mills, Dorian Dervite and Tim Ream. While Andy Lonergan returns between the sticks in place of Adam Bogdan.
Wanderers' new signings Adam Le Fondre and Rochinha are still awaiting international clearance and are unavailable for selection this evening, although the young Portuguese Rochinha has travelled with the squad.
Rotherham have Connor Sammon starting up front alongside former Blackburn man Matt Derbyshire, while former Man United youngster Zeki Fryers starts at left-back. Former Bolton academy product Danny Ward takes his place on the Rotherham bench, alongside Jack Barmby, the son of former Everton striker Nick.
Keep up to date with all the action and have your say on tonight's action in the Comments section below.
Here are tonight's starting lineups.
Substitutes: Tony Thompson, Richard Wood, Richard Brindley, Jordan Bowery, Adam Hammill, Jack Barmby, Danny Ward.
Substitutes: Adam Bogdan, Dean Moxey, Jay Spearing, Liam Trotter, David Wheater, Sanmi Odelusi, Tom Walker.