Born in St Louis, Missouri, Tim Ream began his professional career at the age of 21 with Chicago Fire of MLS, before being drafted in the second round (18th overall) of the 2010 MLS Superdraft by New York Red Bulls. He made his debut in March 2010 in a friendly victory against Brazilian side Santos, in the opening game at the brand new Red Bull Arena.
In December 2011, Ream had impressed to the point where he was invited over to join training camps run by West Bromwich Albion and Bolton Wanderers. At the beginning of January 2012 New York Red Bulls accepted Bolton's £2.5m offer and Ream joined as the replacement for Gary Cahill who had recently left Bolton to join Chelsea.
Ream made his debut in February as Bolton defeated Millwall 2-0 in the FA Cup. However a run of poor form has since led Ream to be a back-up choice at the club. Whilst a full USMNT international with eight caps, he has not been called up to join the squad since the end of the 2011 CONCACAF Gold Cup.